[Nameless_User12]

Do you know any anime similar to Serial Experiments Lain?

[DeadMansPest]

Well it depends on what you consider similar? Do you mean in the overall subject material or the genre.

[ApplePie777]

My Little Pony and Equestria Girls
Nerdy girl in society, just like Twilight Sparkles

Naw fr, Paprika look similar even if they don't give the same mood. Also the anime about the femcel in Highschool that i forgot the name.

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Do you know any anime similar to Serial Experiments Lain?

there is also movie like Lain.
They are more "hard" but you can still look up.
There is Stalker from 1979 and all the movie from the same guy.
Eduard Limonov was also good as it treated society but it isn't the mood and the same topic (there is no informatic)

[ddddethroned]

Ghost in the shell movies and Texhnolyze  gave me the same vibe/aesthetic so maybe you can give them a try

[shadowsword]

Yeah, if you liked Serial Experiments Lain, definitely check out Texhnolyze — same writer, even darker and more nihilistic. Ergo Proxy also has that dystopian cyberpunk vibe with heavy philosophical themes. Boogiepop Phantom and Paranoia Agent are both trippy and psychological. Perfect Blue too if you're into identity breakdowns.